#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.

Publish Date: 2023/8/28

The Peter Attia Drive

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#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.

The Peter Attia Drive

Chapters

What sparked Wendy's interest in genetics as a physician-scientist?

Understanding phenylketonuria (PKU): A deep dive into a rare inherited disorder

How has genetic research evolved from DNA structure to whole genome sequencing?

What were the key insights and surprises from the Human Genome Project?

Exploring different types of genetic tests: What sets them apart?

What is whole genome sequencing and why is it important?

What are the implications of germline mutations for older parents?

Understanding whole exome sequencing and the significance of read depth

How does genetic testing for breast cancer work?

What does direct-to-consumer genetic testing provide?

The GUARDIAN study and the importance of newborn genetic screening

How is genetic disease treated with gene therapy?

The story of Jesse Gelsinger and the challenges of gene therapy

What are the use cases for gene therapy and the differences between gene addition and editing?

Two gene editing strategies for Tay-Sachs and fragile X syndrome

Exploring obesity as a polygenic disease: What role do heritability and epigenetics play?

What are the genetic factors behind autism?

Understanding the genetics of cardiovascular disease

What are the financial and economic considerations of gene therapy?

What are the ethical implications of gene editing?

What does the future hold for clinical genetics?

Shownotes Transcript

PodQuest PodQuest Podcast Discovery Engine tailors playlist for your curiosity

#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D. 02:27:29

The Peter Attia Drive

Chapters

What sparked Wendy's interest in genetics as a physician-scientist?

Understanding phenylketonuria (PKU): A deep dive into a rare inherited disorder

How has genetic research evolved from DNA structure to whole genome sequencing?

What were the key insights and surprises from the Human Genome Project?

Exploring different types of genetic tests: What sets them apart?

What is whole genome sequencing and why is it important?

What are the implications of germline mutations for older parents?

Understanding whole exome sequencing and the significance of read depth

How does genetic testing for breast cancer work?

What does direct-to-consumer genetic testing provide?

The GUARDIAN study and the importance of newborn genetic screening

How is genetic disease treated with gene therapy?

The story of Jesse Gelsinger and the challenges of gene therapy

What are the use cases for gene therapy and the differences between gene addition and editing?

Two gene editing strategies for Tay-Sachs and fragile X syndrome

Exploring obesity as a polygenic disease: What role do heritability and epigenetics play?

What are the genetic factors behind autism?

Understanding the genetics of cardiovascular disease

What are the financial and economic considerations of gene therapy?

What are the ethical implications of gene editing?

What does the future hold for clinical genetics?

Shownotes Transcript

PodQuest PodQuest Podcast Discovery Engine tailors playlist for your curiosity

#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.