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The Peter Attia Drive
#207 - AMA #35: "Anti-Aging" Drugs — NAD+, metformin, & rapamycin
30:32
Publish Date:
2022/5/16
The Peter Attia Drive
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Chapters
What is the logic behind comparing NAD precursors to rapamycin and metformin?
What are the current state, usefulness, and future promise of aging biomarkers?
What are epigenetic clocks, their use cases, and limitations?
What are the advantages and limitations of studying aging in non-humans?
Why is the importance of control lifespans crucial in aging studies?
What is the potential role of NAD in aging and its relationship to sirtuins?
What is the current data on NAD precursors (NR and NMN)?
What are the findings from human studies with NAD precursors?
How do NAD lifespan data compare to data from metformin and rapamycin?
What defines a 'clean drug' and a 'dirty drug'?
Why are there fewer rapamycin studies in humans compared to NAD and metformin?
How do the geroprotective molecules rank in terms of risk and reward?
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